Subcellular Biochemistry, Volume 43

افزودن به بوکمارک اشتراک گذاری 0 دیدگاه کاربران 5 (0)

Subcellular Proteomics: From Cell Deconstruction to System Reconstruction

مشارکت: عنوان و توضیح کوتاه هر کتاب را ترجمه کنید این ترجمه بعد از تایید با نام شما در سایت نمایش داده خواهد شد.

ترجمه این کتاب مشاهده همه کتاب های ترجمه نشده

Subcellular Proteomics: From Cell Deconstruction to System Reconstruction

As proteomics technologies are reaching a plateau in the number of proteins that can beresolvedanddetected, pre-fractionationstepshavebecomeessentialtoincreasethe depth of proteomic analysis. So far, many pre-fractionation steps have been based on chromatography methods where the proteins are separated according to their indiv- ual physicochemical properties. Subcellular fractionation methods proved to be very potentproteinpre-fractionationsteps: theyallowtherepresentationoflowabundance proteins, andtheycanbecombinedwithchromatographysteps. Moreover, asthei- latedsubcellularcomponentsalsorepresentfunctionalunits, subcellularfractionation allows the proteomic analysis of protein subsets that are functionally related in a b- logically relevant manner. The first three sections of this volume deal with different levels of subcellular organization that also correspond to specific methodological approaches. In his keynote chapter, Thierry Rabilloud superbly introduces the first section with athoroughdefinitionofmembraneproteomicswherehepinpointskeytheoreticaland practicalissuesofthisfield, therebysettingthestageforthenextcontributions.Miguet et al. address the first key issue: the quality of the membrane preparation; they int- duce and validate a microparticle strategy for plasma membrane purification. Zahedi et al. deal with the second major issue, the resolving of the hydrophobic proteins found in biological membrane samples, which they solve through two-dimensional BAC/SDS-PAGE gel electrophoresis. To close the first section, Foster and Chan review the proteomics of lipid rafts, membrane structures that are involved in int- cellular trafficking and signal transduction. They describe a clever validation scheme based on the sensitivity of lipid rafts to cholesterol disruption. Acentral theme in the second section on organelle subproteomes is the variability of their composition and how it can be exploited and interpreted. Kavanagh et

لغو

گزارش تخلف

مغایرت عنوان کتاب با توضیحات و تصویر جلد
عدم رعایت حقوق نشر طبق قوانین جمهوری اسلامی ایران
محتوای مستهجن
توهین به قومیتها و محتوای نژادپرستی
توهین به اقیلیتهای مذهبی
اهانت به مقامات سیاسی و مذهبی
اشاعه ی کودک آزاری
سایر موارد

بستن

فرمت کتاب

ebook

زبان

english

تاریخ انتشار

2007

نویسنده

Eric Bertrand

ناشر

Springer

شابک

9781402059421

20,000 تومان

خرید کتاب مطالعه نمونه درخواست ترجمه کتاب

خرید کتاب Subcellular Biochemistry, Volume 43

Subcellular Biochemistry, Volume 43

گزارش تخلف

فرمت کتاب

ebook

زبان

english

تاریخ انتشار

2007

نویسنده

ناشر

شابک

کتاب های مرتبط

Thermodynamics in Bioenergetics

Contemporary Metabolism

Purine and Pyrimidine Metabolism in Man VIII

Biochemistry and Molecular Biology of Antimicrobial Drug Action

Dynamics of Biochemical Systems.

Methods in Membrane Biology. Volume 6

Life Chemistry Research

Methods in Molecular Biology, Volume 228

The Role of Microtubules in Cell Biology, Neurobiology, and Oncology [With CDROM]

Molecular Targeting in Oncology (Cancer Drug Discovery and Development)

Comparative Genomics

The physiology and biochemistry of prokaryotes

Allostery

Protein Expression in Mammalian Cells

Vaccinia Virus and Poxvirology

Biomass Conversion

Data Mining in Proteomics

Marks' Basic Medical Biochemistry

Peptide Modifications to Increase Metabolic Stability and Activity

Parasitic Nematodes

New Frontiers in Chemical Biology

دیدگاه کاربران